FIGURE 1. Thirty-one years of hunting the testis-determining factor. The chromosomal region thought to include the elusive factor is shaded. The search has narrowed from 30-40 million bases (1959) to less than to 250 bases encoding for the conserved 80-amino-acid motif of SRY (1990). See text for further explanation. Source: McLaren (30).
Edited by Aldo Campana,