Curative in localized disease

Radical prostatectomy (total extirpation of the prostate with the seminal vesicles and vesico-urethral anastomosis). Consequence: 50% of patients are impotent

Radical radiotherapy

Palliative in metastatic disease

Hormonal (antiandrogenic) treatment: surgical castration, GnRH in combination with a non-steroidal antiandrogen