Developmental and genetic diseases

*Gene map locus 4q21

AI1B

AIH2

Amelogenesis imperfecta, hypoplastic local, autosomal dominant

Enamel hypoplasia, hereditary localized

[Clinical features: hypoplastic amelogenesis imperfecta; horizontal row of pits, linear depressions, or one large hypoplastic area in the enamel with hypocalcification of the enamel adjacent to and below the hypoplastic area]

[Inheritance: autosomal dominant]