Developmental and genetic diseases

*Gene map locus 15q21.1

Craniosynostosis with arachnodactyly and abdominal hernias

Marfanoid craniosynostosis syndrome

Marfanoid disorder with craniosynostosis, type I

SGS

Shprintzen-Goldberg syndrome

[Clinical features: craniosynostosis; distinctive craniofacial features; skeletal changes (dolichostenomelia, arachnodactyly, camptodactyly, pes planus, pectus excavatum or carinatum, scoliosis, joint hypermobility, or contractures); neurologic abnormalities; mild-to-moderate mental retardation; brain anomalies (hydrocephalus, dilatation of the lateral ventricles, and Chiari 1 malformation)]

[Inheritance: isolated cases]