Infertility, miscarriage, ectopic pregnancy

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Assisted reproductive technology: pregnancy outcomes

Canada

• Canadian Fertility & Andrology Society
  • Recurrent implantation failure in IVF: A Canadian Fertility and Andrology Society Clinical Practice Guideline [2020]
  • Management of thin endometrium in assisted reproduction: a clinical practice guideline from the Canadian Fertility and Andrology Society [2019]
  • Increased risk of preterm birth in singleton pregnancies after blastocyst versus Day 3 embryo transfer: Canadian ART Register (CARTR) analysis [2013]

• Journal of Obstetrics and Gynaecology Canada
  • Severe Maternal Morbidity and Maternal Mortality Associated with Assisted Reproductive Technology [2022]

• Society of Obstetricians and Gynaecologists of Canada
  • Pregnancy Outcomes After Assisted Human Reproduction [2014]

China

• Frontiers in Endocrinology
  • Placental Abnormalities and Placenta-Related Complications Following In-Vitro Fertilization: Based on National Hospitalized Data in China [2022]

• PLoS ONE
  • Live Birth Sex Ratio after In Vitro Fertilization and Embryo Transfer in China - An Analysis of 121,247 Babies from 18 Centers [2014]

Estonia

• BMC Pregnancy and Childbirth
  • Singleton pregnancies after in vitro fertilization in Estonia: a register-based study of complications and adverse outcomes in relation to the maternal socio-demographic background [2019]

Europe

• European Society of Human Reproduction and Embryology
  • ESHRE good practice recommendations on recurrent implantation failure [2023]
  • Outcomes of SARS-CoV-2 infected pregnancies after medically assisted reproduction [2021]
  • Birth defects and congenital health risks in children conceived through assisted reproduction technology (ART): a meeting report [2014]

Finland

• Acta Diabetologica
  • In vitro fertilization increases the odds of gestational diabetes: a nationwide register-based cohort study [2023]

International

• BMC Pregnancy and Childbirth
  • Embryonic and neonatal outcomes following double vitrification/thawing: a systematic review and meta-analysis [2025]
  • Assisted reproductive technology and hypertensive disorders of pregnancy: systematic review and meta-analyses [2021]
  • Assisted reproductive technology and the risk of preeclampsia: an updated systematic review and meta-analysis [2019]

• Fertility and Sterility
  • Current evidence supporting a goal of singletons: a review of maternal and perinatal outcomes associated with twin versus singleton pregnancies after in vitro fertilization and intracytoplasmic sperm injection [2020]

• Frontiers in Endocrinology
  • The influence of embryo stage on obstetric complications and perinatal outcomes following programmed compared to natural frozen-thawed embryo transfer cycles: a systematic review and meta-analysis [2023]

• Human Fertility
  • Obstetric and perinatal outcomes in singleton pregnancies following medicated, stimulated and natural, frozen embryo transfer cycles: an updated systematic review and meta-analysis [2025]

• Human Reproduction
  • Day 5 versus Day 6 blastocyst transfers: a systematic review and meta-analysis of clinical outcomes [2019]

• International Federation of Gynecology and Obstetrics
  • FIGO good practice recommendations on reduction of preterm birth in pregnancies conceived by assisted reproductive technologies [2021]

• International Journal of Environmental Research and Public Health
  • Evaluation of the Risk of Birth Defects Related to the Use of Assisted Reproductive Technology: An Updated Systematic Review [2022]

• JBRA Assisted Reproduction
  • In Vitro Fertilisation and Intracytoplasmic Sperm Injection predictive factors: A review of the effect of female age, ovarian reserve, male age, and male factor on IVF/ICSI treatment outcomes [2023]

• Medicina
  • Fresh versus Frozen Embryo Transfer in In Vitro Fertilization/Intracytoplasmic Sperm Injection Cycles: A Systematic Review and Meta-Analysis of Neonatal Outcomes [2024]

• Reproductive Biology and Endocrinology
  • Effect of endometrial thickness on obstetric and neonatal outcomes in assisted reproduction: a systematic review and meta-analysis [2023]

• Ultrasound in Obstetrics & Gynecology
  • Congenital anomaly and perinatal outcome following blastocyst- vs cleavage-stage embryo transfer: systematic review and network meta-analysis [2023]

Japan

• Environmental Health and Preventive Medicine
  • Birth defects after assisted reproductive technology according to the method of treatment in Japan: nationwide data between 2004 and 2012 [2015]

• European Journal of Pediatrics
  • In vitro fertilization and long-term child health and development: nationwide birth cohort study in Japan [2024]

• Journal of Assisted Reproduction and Genetics
  • Down syndrome live births following assisted reproductive technology in Japan: a nationwide survey between 2007 and 2016 [2022]

Nordic countries

• Fertility and Sterility
  • Risk of stillbirth and neonatal death in singletons born after fresh and frozen embryo transfer: cohort study from the Committee of Nordic Assisted Reproduction Technology and Safety [2023]

Republic of Korea

• Clinical and Experimental Reproductive Medicine
  • Multiple pregnancy after single or multiple embryo transfer performed according to Korean guidelines [2015]

• Fertility and Sterility
  • Neurodevelopmental outcomes of preterm infants with very low birth weight conceived with the assistance of in vitro fertilization [2022]

• PLoS ONE
  • Effects of assisted reproductive technology on severe maternal morbidity risk in both singleton and multiple births in Korea: A nationwide population-based cohort study [2022]

Sweden

• Fertility and Sterility
  • Mortality from infancy to adolescence in singleton children conceived from assisted reproductive techniques versus naturally conceived singletons in Sweden [2020]

• Frontiers in Endocrinology
  • The association between body mass index and live birth and maternal and perinatal outcomes after in-vitro fertilization: a national cohort study [2023]

Taiwan

• Frontiers in Endocrinology
  • Embryo transfer impact: a comprehensive national cohort analysis comparing maternal and neonatal outcomes across varied embryo stages in fresh and frozen transfers [2024]

• Frontiers in Pediatrics
  • Children Conceived by Assisted Reproductive Technology Prone to Low Birth Weight, Preterm Birth, and Birth Defects: A Cohort Review of More Than 50,000 Live Births During 2011–2017 in Taiwan [2020]

United Kingdom

• BMC Medicine
  • Live birth rates and perinatal outcomes when all embryos are frozen compared with conventional fresh and frozen embryo transfer: a cohort study of 337,148 in vitro fertilisation cycles [2019]

• Fertility and Sterility
  • Comparison of perinatal outcomes after frozen or fresh embryo transfer: separate analyses of singleton, twin, and sibling live births from a linked national in vitro fertilization registry [2022]

• Health Technology Assessment
  • Transfer of thawed frozen embryo versus fresh embryo to improve the healthy baby rate in women undergoing IVF: the E-Freeze RCT [2022]

• Royal College of Obstetricians and Gynaecologists
  • Multiple Pregnancy Following Assisted Reproduction [2018]
  • Epigenetics and Reproductive Medicine [2018]

• UK Maternal Cardiology Society
  • Best practice recommendations for medically assisted reproduction in patients with known cardiovascular disease or at high risk of cardiovascular disease [2024]

United States

• American College of Obstetricians and Gynecologists
  • Perinatal Risks Associated With Assisted Reproductive Technology [2016]

• American Society for Reproductive Medicine
  • The role of immunotherapy in in vitro fertilization: a guideline [2018]

• Centers for Disease Control and Prevention
  • Births resulting from assisted reproductive technology: comparing birth certificate and National ART Surveillance System Data, 2011 [2014]

• F&S Reports
  • Effects of parity on preterm delivery in twin gestations conceived with in vitro fertilization [2023]

• Fertility and Sterility
  • Trends and outcomes of fresh and frozen donor oocyte cycles in the United States [2024]
  • Embryo transfer practices and multiple births resulting from assisted reproductive technology: an opportunity for prevention [2015]
  • Elective single embryo transfer trends and predictors of a good perinatal outcome—United States, 1999–2010 [2013]

• Human Reproduction
  • The risks of birth defects and childhood cancer with conception by assisted reproductive technology [2022]

• JAMA Network Open
  • Assessment of Birth Defects and Cancer Risk in Children Conceived via In Vitro Fertilization in the US [2020]

• Journal of Assisted Reproduction and Genetics
  • Recurrence risk and risk factors for monozygotic twin and triplet birth in over 65,000 single-embryo transfers [2023]

• New England Journal of Medicine
  • Fertility Treatments and Multiple Births in the United States [2013]

• Reproductive Biology and Endocrinology
  • Time associations between U.S. birth rates and add-Ons to IVF practice between 2005–2016 [2021]

• Society for Assisted Reproductive Technology
  • Frozen autologous and donor oocytes are associated with differences in clinical and neonatal outcomes compared with fresh oocytes: a Society for Assisted Reproductive Technology Clinic Outcome Reporting System Analysis [2023]
  • Association between embryo morphological quality and birth weight for singletons conceived via autologous fresh embryo transfer: an analysis using Society for Assisted Reproductive Technology Clinical Outcomes Reporting System [2022]
  • Adherence to embryo transfer guidelines in favorable-prognosis patients aged less than 35 years using autologous oocytes and in recipients using donor oocytes: a Society for Assisted Reproductive Technology Clinic Outcome Reporting System study [2022]
  • The incidence of ectopic/heterotopic pregnancies after blastocyst-stage frozen-thawed embryo transfers compared with that after cleavage-stage: a Society for Assisted Reproductive Technologies Clinical Outcomes Reporting System study [2021]
  • Obstetric outcomes in pregnancies resulting from in vitro fertilization are not different in fertile, sterilized women compared to infertile women: A Society for Assisted Reproductive Technology database analysis [2021]
  • Increased male live-birth rates after blastocyst-stage frozen-thawed embryo transfers compared with cleavage-stage frozen-thawed embryo transfers: a SART registry study [2021]
  • Elective transfer of one embryo is associated with a higher cumulative live birth rate and improved perinatal outcomes compared to the transfer of two embryos with in vitro fertilization [2020]

• Society for Maternal-Fetal Medicine
  • Society for Maternal-Fetal Medicine Special Statement: Checklist for pregnancies resulting from in vitro fertilization [2022]
  • Society for Maternal-Fetal Medicine Consult Series #60: Management of pregnancies resulting from in vitro fertilization [2022]

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• Topic
  • Assisted reproductive technology