FIGURE 2. The pharmacokinetics of a new long-acting testosterone ester, testosterone buciclate, offers good substitution therapy for male hypogonadism and the promise of a 3 or 4 times a year injectable method of contraception for normal men (4).
Single dose im injections of 200mg (open triangles) or 600 mg (filled circles) testosterone buciclate to hypogonadal men.
Upper panel: serum concentrations (mean ± SEM) of androgen (some of testosterone and dihydrotestosterone), broken line indicates the lower normal limit;
Middle panel: testosterone increase over basal value;
Lower panel: dihydrotestosterone concentrations, broken line indicates upper normal limit.
Edited by Aldo Campana,