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TABLE 1. One-year life-table discontinuation rates per 100 women, with different injectable hormonal contraceptives.

Method

(Reference)

Women-months

Pregnancy

Amenorrhea

Bleeding

All Reasons

3-Monthly Injectable

DMPA 150

(9)

20,550

0.10

11.9

15.0

51.4

DMPA 150

(8)

4,782

0.7

11.5

9.3

28.8

DMPA 150

(10)

5,429

0

12.5

13.3

41.2

2-Monthly Injectable

NET-EN 200

(9)

10,361

0.4

6.8

13.6

49.7

NET-EN 200

(1)

4,101

1.1

6.9

14.8

35.7

NET-EN 200

(WHO unpub.)

1,445

0

4.5

9.8

42.0

Once-a-month Injectables

DMPA 25/E2 Cyp 5

(12)

10,969

0

2.1

6.3

35.5

DMPA 25/E2 Cyp 5

(5)

19,765

0.1

5.2

12.7

26.4

NET-EN 50/E2 Val 5

(12)

10,608

0.2

1.6

7.5

36.8

NET-EN 50/E2 Val 5

(5)

20,688

0.3

0.8

7.9

18.8

NET-EN 50/E2 Val 5

(1)

3,716

0.2

4.2

12.0

44.1

17-OH-P Cap 250/E2 Val 5

(5)

10,459

0.8

0.7

12.6

20.4

Note: Cyp, cypionate; DMPA, depot-medroxyprogesterone acetate; E2, estradiol;

NET-EN, norethisterone enanthate; Val, valerate; 17-OH P Cap, 17-hydroxyprogesterone caproate.