Obesity, eating disorders

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Obesity: pharmacologic treatment

Australia

• Australian Family Physician
  • Pharmacotherapy for obesity [2017]

• Australian Journal of General Practice
  • Pharmacotherapy for the management of overweight and obesity [2025]
  • Glucagon-like peptide-1 receptor agonists for weight loss: Consider the case for selective pharmacotherapy [2025]
  • New anti-obesity medications: Considerations and future directions in people with concurrent eating disorders [2023]

• Australian Prescriber
  • Medicines for long-term obesity management [2022]

Canada

• Canadian Agency for Drugs and Technologies in Health
  • Pharmacoeconomic Review Report: Naltrexone Hydrochloride and Bupropion Hydrochloride (Contrave) [2020]
  • Clinical Review Report: Naltrexone Hydrochloride and Bupropion Hydrochloride (Contrave) [2020]
  • CADTH Canadian Drug Expert Committee Recommendation: Naltrexone Hydrochloride and Bupropion Hydrochloride (Contrave — Bausch Health, Canada Inc.) [2020]

• Canadian Family Physician
  • Weight normativity in action: Semaglutide and obesity [2025]

• Canadian Journal of Public Health
  • Drivers of medicalization in the Canadian Adult Obesity Clinical Practice Guidelines [2022]

• Obesity Canada
  • Pharmacotherapy in Obesity Management [2022]

Europe

• European Association for the Study of Obesity
  • 2014 EASO Position Statement on the Use of Anti-Obesity Drugs [2015]

• European Medicines Agency
  • Clinical evaluation of medicinal products used in weight control - Scientific guideline

• Pharmacology Research & Perspectives
  • Analysis of Reporting Trends of Serious Adverse Events Associated With Anti-Obesity Drugs [2025]

Europe, United States

• Diabetes, Metabolic Syndrome and Obesity
  • The Efficacy of GLP-1 Analogues on Appetite Parameters, Gastric Emptying, Food Preference and Taste Among Adults with Obesity: Systematic Review of Randomized Controlled Trials [2023]

International

• American Journal of Cardiology
  • Long-Term Efficacy and Safety of Once-Weekly Semaglutide for Weight Loss in Patients Without Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials [2024]

• BMC Medicine
  • Post-marketing withdrawal of anti-obesity medicinal products because of adverse drug reactions: a systematic review [2016]

• Current Obesity Reports
  • Long-Term Efficacy and Safety of Anti-Obesity Treatment: Where Do We Stand? [2021]

• Diabetes, Metabolic Syndrome and Obesity
  • Semaglutide 2.4 Mg for the Management of Overweight and Obesity: Systematic Literature Review and Meta-Analysis [2022]

• Diabetology & Metabolic Syndrome
  • The best drug supplement for obesity treatment: a systematic review and network meta-analysis [2021]

• Frontiers in Endocrinology
  • The effects of subcutaneous Tirzepatide on obesity and overweight: a systematic review and meta-regression analysis of randomized controlled trials [2023]

• Pediatric Obesity
  • Considerations for the design and conduct of pediatric obesity pharmacotherapy clinical trials: Proceedings of expert roundtable meetings [2024]

Ireland

• Association for the Study of Obesity on the Island of Ireland
  • Pharmacotherapy in Obesity Management [2022]

Latin America

• Obesity Reviews
  • Consensus on pharmacological treatment of obesity in Latin America [2024]

Norway

• Diabetes, Obesity and Metabolism
  • Pharmacological treatment of obesity in adults in Norway 2004-2022 [2024]

Poland

• Nutrition, Obesity & Metabolic Surgery
  • Treatment of overweight and obesity during and after a pandemic. Let’s not wait for the development of complications – new guidelines for doctors [2020]

Republic of Korea

• Journal of Global Health
  • A nationwide pharmacovigilance investigation on trends and seriousness of adverse events induced by anti-obesity medication [2023]

Saudi Arabia

• Scientific World Journal
  • Safety Evaluation of Local Weight-Gain Formulas in the Saudi Arabian Markets [2015]

United Kingdom

• Advances in Therapy
  • Once-Weekly Subcutaneous Semaglutide 2.4 mg Injection is Cost-Effective for Weight Management in the United Kingdom [2023]

• Health Technology Assessment
  • The quantity, quality and findings of network meta-analyses evaluating the effectiveness of GLP-1 RAs for weight loss: a scoping review [2025]

• National Institute for Health and Care Excellence
  • Tirzepatide for managing overweight and obesity [2024]
  • Semaglutide for managing overweight and obesity [2023]
  • Liraglutide for managing overweight and obesity [2020]
  • Naltrexone–bupropion for managing overweight and obesity [2017]

• Right Decisions
  • Drugs Used in the Treatment of Obesity

United States

• AMA Journal of Ethics
  • Should Pharmaceuticals Be Used as Weight Loss Interventions for Adolescents Classified as Obese by BMI? [2023]

• American Family Physician
  • Semaglutide (Wegovy) for the Treatment of Obesity [2023]

• American Gastroenterological Association
  • AGA Clinical Practice Guideline on Pharmacological Interventions for Adults With Obesity [2022]

• American Journal of Health Promotion
  • The Critical Role of Lifestyle With the Use of Contemporary Obesity Management Medications [2025]
  • Building Comprehensive Care Networks to Support Lifestyle Change in Patients Taking Obesity Management Medications [2025]

• Centers for Disease Control and Prevention
  • Prescriptions for Obesity Medications Among Adolescents Aged 12–17 Years with Obesity — United States, 2018–2023 [2025]

• Cleveland Clinic Journal of Medicine
  • Pharmacotherapy for obesity: What you need to know [2017]

• Current Opinion in Endocrinology, Diabetes and Obesity
  • Pharmacotherapy in Pediatric Obesity: Current Evidence and Landscape [2021]

• EClinicalMedicine
  • Pharmacotherapy of obesity: an update on the available medications and drugs under investigation [2023]

• Endocrine Practice
  • Anti-obesity Medication Use Among Adults with Overweight and Obesity in the United States: 2015–2018 [2021]

• Endocrine Society
  • Pharmacological management of obesity: an Endocrine Society clinical practice guideline [2015]

• Endotext
  • Pharmacologic Treatment of Overweight and Obesity in Adults

• Expert Opinion on Drug Safety
  • The risk of cardiovascular complications with current obesity drugs [2020]

• Expert Opinion on Pharmacotherapy
  • The limits and challenges of antiobesity pharmacotherapy [2020]
  • Anorectic state of obesity medications in the United States. Are leaner times ahead? [2020]

• Institute for Clinical and Economic Review
  • Obesity Management

• JAMA
  • Association of Pharmacological Treatments for Obesity With Weight Loss and Adverse Events: A Systematic Review and Meta-analysis [2016]

• JAMA Health Forum
  • Lifetime Health Effects and Cost-Effectiveness of Tirzepatide and Semaglutide in US Adults [2025]

• JAMA Network Open
  • Older Adults' Views on Insurance Coverage for Weight Management Medications [2025]
  • Cost-Effectiveness of Pharmacotherapy for the Treatment of Obesity in Adolescents [2023]

• Journal of Managed Care & Specialty Pharmacy
  • Cost-effectiveness analysis of semaglutide 2.4 mg for the treatment of adult patients with overweight and obesity in the United States [2022]

• Journal of the Endocrine Society
  • An Updated Approach to Antiobesity Pharmacotherapy: Moving Beyond the 5% Weight Loss Goal [2023]

• Journal of Women's Health
  • Obstetrician-Gynecologists' Strategies for Patient Initiation and Maintenance of Antiobesity Treatment with Glucagon-Like Peptide-1 Receptor Agonists [2021]

• Methodist DeBakey Cardiovascular Journal
  • Medical Management of Obesity: Current Trends and Future Perspectives [2025]

• National Academies of Sciences, Engineering, and Medicine
  • Medications and Obesity: Exploring the Landscape and Advancing Comprehensive Care: Proceedings of a Workshop [2024]

• Nutrition & Diabetes
  • An algorithm for the use of anti-obesity medications [2024]

• Obesity
  • Treatment of obesity: Pharmacotherapy trends in the United States from 1999 to 2010 [2015]

• Obesity Pillars
  • Clinical review: Guide to pharmacological management in pediatric obesity medicine [2023]

• StatPearls
  • Pharmacologic Therapy for Obesity
  • Orlistat

• Turkish Journal of Medical Sciences
  • Paradigm shift in obesity treatment: an extensive review of current pipeline agents [2025]

• U.S. Department of Health and Human Services - Office of the Assistant Secretary for Planning and Evaluation
  • Medicare Coverage of Anti-Obesity Medications [2024]

• U.S. Department of Veterans Affairs
  • Weight Management Medications for Chronic Use [2024]

{Related topics}

• Topic
  • Obesity