Obstetrics, gynecology and reproductive medicine guidelines

Pregnancy

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Rh isoimmunization

 

Australia

• Australian Red Cross Blood Service
  • Haemolytic disease of the newborn

• Medical Services Advisory Committee
  • Non-Invasive Prenatal Testing (NIPT) for fetal Rhesus D genotype [2019]

• National Blood Authority
  • Prophylactic use of Rh D immunoglobulin in pregnancy care [2021]

• NSW Health
  • Rh (D) Immunoglobulin (Anti D) [2015]

Canada

• Canadian Family Physician
  • Approach to red blood cell antibody testing during pregnancy [2020]

• Health Quality Ontario
  • Noninvasive Fetal RhD Blood Group Genotyping: A Health Technology Assessment [2020]

• Society of Obstetricians and Gynaecologists of Canada
  • Prevention of Rh Alloimmunization [2018]
  • Routine Non-invasive Prenatal Prediction of Fetal RHD Genotype in Canada: The Time is Here [2017]

International

• BMC Pregnancy and Childbirth
  • Targeted antenatal anti-D prophylaxis for RhD-negative pregnant women: a systematic review [2020]
  • Appropriate provision of anti-D prophylaxis to RhD negative pregnant women: a scoping review [2014]

• International Federation of Gynecology and Obstetrics
  • FIGO/ICM guidelines for preventing Rhesus disease: A call to action [2021]

• Pediatric Research
  • Neonatal hyperbilirubinemia and Rhesus disease of the newborn: incidence and impairment estimates for 2010 at regional and global levels [2013]

Ireland

• Ireland's Health Services
  • Anti D immunoglobin for the prevention of RHD Haemolytic disease of the newborn [2012]

Italy

• Società Italiana di Medicina Trasfusionale e Immunoematologia
  • Recommendations for the prevention and treatment of haemolytic disease of the foetus and newborn [2015]
  • Survey on the prevention and incidence of haemolytic disease of the newborn in Italy [2013]

Netherlands

• BMJ
  • Sensitivity of fetal RHD screening for safe guidance of targeted anti-D immunoglobulin prophylaxis: prospective cohort study of a nationwide programme in the Netherlands [2016]

• Transfusion
  • Reduction of anti-K-mediated hemolytic disease of newborns after the introduction of a matched transfusion policy: A nation-wide policy change evaluation study in the Netherlands [2021]

New Zealand

• New Zealand College of Midwives
  • Anti-D prophylaxis administration during pregnancy and early postpartum [2021]

• Starship
  • Hydrops fetalis [2020]

United Kingdom

• BMC Pregnancy and Childbirth
  • Routine administration of Anti-D: the ethical case for offering pregnant women fetal RHD genotyping and a review of policy and practice [2014]

• British Society for Haematology
  • Guideline for blood grouping and red cell antibody testing in pregnancy [2016]
  • BCSH guideline for the use of anti-D immunoglobulin for the prevention of haemolytic disease of the fetus and newborn [2014]

• Health Technology Assessment
  • High-throughput non-invasive prenatal testing for fetal rhesus D status in RhD-negative women not known to be sensitised to the RhD antigen: a systematic review and economic evaluation [2018]

• National Institute for Health and Care Excellence
  • High-throughput non-invasive prenatal testing for fetal RHD genotype [2016]
  • Routine antenatal anti-D prophylaxis for women who are rhesus D negative [2008]

• NHS England
  • Management of fetal anaemia secondary to red cell alloimmunisation [2015]

United States

• Society for Maternal-Fetal Medicine
  • Society for Maternal-Fetal Medicine (SMFM) Clinical Guideline #8: The fetus at risk for anemia–diagnosis and management [2015]

• Transfusion
  • It’s time to phase-in RHD genotyping for patients with a serological weak D phenotype [2014]

• U.S. Preventive Services Task Force
  • Rh(D) Incompatibility: Screening [2004]

{Related topics}

• Guidelines
  • Prenatal screening and diagnosis
  • Obstetrics, perinatology