HIV/AIDS

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Post-exposure prophylaxis

Americas

• Pan American Health Organization
  • Post-Exposure Prophylaxis (PEP)

Asia, Sub-Saharan Africa

• Journal of the International AIDS Society
  • Occupational post-exposure prophylaxis among healthcare workers: a scoping review of factors affecting optimal utilization [2024]

Australia

• Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine
  • Prescribing HIV post-exposure prophylaxis (PEP) in Australia
  • PEP Guidelines

• Queensland Health
  • Initiating post-exposure prophylaxis after non-occupational and occupational exposure to HIV

Belgium

• PLoS ONE
  • Prescription of Non-Occupational Post-Exposure HIV Prophylaxis by Emergency Physicians: An Analysis on Accuracy of Prescription and Compliance [2016]

Canada

• British Columbia Centre for Excellence in HIV/AIDS
  • HIV Post-Exposure Prophylaxis (PEP) Guidelines

• Canadian Family Physician
  • Post-exposure prophylaxis-in-pocket for HIV prevention [2024]

Eswatini

• Journal of the International AIDS Society
  • Factors associated with PEP awareness among adolescent girls and young women in Eswatini [2025]

Hong Kong

• Centre for Health Protection
  • Recommendations on the use of non-occupational post-exposure prophylaxis against HIV [2018]

International

• Clinical Infectious Diseases
  • Formulating the Future Research Agenda for Postexposure Prophylaxis for HIV: Methodological Challenges and Potential Approaches [2015]
  • End Users’ Views and Preferences on Prescribing and Taking Postexposure Prophylaxis for Prevention of HIV: Methods to Support World Health Organization Guideline Development [2015]

• Journal of the International AIDS Society
  • HIV post-exposure prophylaxis in community settings and by lay health workers or through task sharing: a systematic review of effectiveness, case studies, values and preferences, and costs [2025]
  • Updated guidelines on HIV post-exposure prophylaxis: continued efforts towards increased accessibility [2024]

Ireland

• Health Protection Surveillance Centre
  • Guidelines for the Emergency Management of Injuries and Post-Exposure Prophylaxis (PEP)

• Sexually Transmitted Infections
  • Post-exposure prophylaxis, STI testing and factors associated with follow-up attendance: a review of 4159 cases of acute post-sexual assault medical care [2024]

Kenya, Uganda

• Journal of the International AIDS Society
  • Uptake and patterns of PEP use within the context of a dynamic choice HIV prevention model in rural Uganda and Kenya: SEARCH Study [2025]

Low and middle income countries

• Journal of the International AIDS Society
  • A global review of national guidelines of post-exposure prophylaxis for the prevention of HIV [2025]

Malawi

• Journal of the International AIDS Society
  • Characteristics of individuals who received post-exposure prophylaxis and HIV seroconversion in Malawi: an analysis of national routine HIV testing data [2025]

Mozambique

• Journal of the International AIDS Society
  • Healthcare provider recommendations to improve post-violence care HIV post-exposure prophylaxis access and adherence in Mozambique [2025]

Nigeria

• International Journal of Maternal and Child Health and AIDS
  • HIV Non-Occupational Post Exposure Prophylaxis in Nigeria: A Systematic Review of Research Evidence and Practice [2019]

South Africa

• National Department of Health South Africa
  • National Clinical Guidelines of Post-Exposure Prophylaxis (PEP) in Occupational and Non-Occupational Exposures 2020 [2020]

• South African Family Practice
  • Post-exposure prophylaxis for sexual assault victim-survivors: Guidelines and best practices [2025]

• Southern African HIV Clinicians Society
  • Southern African HIV Clinicians Society 2023 Guideline for post-exposure prophylaxis: Updated recommendations [2023]

Sub-Saharan Africa

• Journal of the International AIDS Society
  • Untapped potential of post-exposure prophylaxis in sub-Saharan Africa: a comparative analysis of PEP implementation planning in Kenya, Mozambique, Nigeria, Uganda and Zambia [2025]
  • Poor post-exposure prophylaxis completion despite improvements in post-violence service delivery in 14 PEPFAR-supported sub-Saharan African countries, 2018-2023 [2025]
  • Implementing the new WHO guidelines on HIV post-exposure prophylaxis: perspectives from five African countries [2025]
  • How plausible is it that PEP would be cost-effective in sub-Saharan Africa? [2025]

Switzerland

• Nature Communications
  • Data linkage to evaluate the long-term risk of HIV infection in individuals seeking post-exposure prophylaxis [2021]

United Kingdom

• British Association for Sexual Health and HIV
  • UK guideline for the use of HIV post-exposure prophylaxis 2021 [2022]

• Department of Health and Social Care
  • EAGA guidance on HIV post-exposure prophylaxis

United States

• American Journal of Infection Control
  • Experiences of the National Post-Exposure Prophylaxis Hotline (PEPline): Occupational PEP consultation needs and trends, 2014 to 2022 [2024]

• Centers for Disease Control and Prevention
  • Antiretroviral Postexposure Prophylaxis After Sexual, Injection Drug Use, or Other Nonoccupational Exposure to HIV — CDC Recommendations, United States, 2025 [2025]
  • Updated guidelines for antiretroviral postexposure prophylaxis after sexual, injection drug use, or other nonoccupational exposure to HIV—United States, 2016 [2016]

• Infectious Disease Clinics of North America
  • Prevention of HIV/AIDS: Post-Exposure Prophylaxis (including Healthcare Workers) [2014]

• National HIV Curriculum
  • Occupational Postexposure Prophylaxis
  • Nonoccupational Postexposure Prophylaxis

• National Institutes of Health
  • HIV Prevention Guidelines on Post-Exposure Prophylaxis (PEP)

• New York State Department of Health AIDS Institute
  • PEP to Prevent HIV Infection

WHO

• World Health Organization
  • Guidelines for HIV post-exposure prophylaxis [2024]
  • Guidelines on post-exposure prophylaxis for HIV and the use of co-trimoxazole prophylaxis for HIV-related infections among adults, adolescents and children: recommendations for a public health approach: December 2014 supplement to the 2013 consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection [2014]
  • Post-exposure prophylaxis to prevent HIV infection : joint WHO/ILO guidelines on post-exposure prophylaxis (PEP) to prevent HIV infection [2007]

{Related topics}

• Topic
  • HIV prevention
  • Antiretroviral therapy