HIV/AIDS

PubMed Free Full Text

Pre-exposure prophylaxis

Africa

• Journal of the International AIDS Society
  • PrEP implementation research in Africa: what is new? [2016]

Americas

• Pan American Health Organization
  • Pre-Exposure Prophylaxis (PrEP)

Asia-Pacific

• Journal of the International AIDS Society
  • PrEP implementation in the Asia-Pacific region: opportunities, implementation and barriers [2016]

• WHO Western Pacific Region
  • Second National Consultation on the Use of Antiretroviral Pre-exposure Prophylaxis (PrEP) to Prevent HIV Acquisition, 4 June 2018, Kuala Lumpur, Malaysia : meeting report [2019]

Australia

• AIDS and Behavior
  • Ending HIV Transmission in Australia: Expanding PrEP to Cisgender Women: A Scoping Review [2024]

• Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine
  • PrEP Guidelines

• Australian Journal of General Practice
  • Prescribing pre exposure prophylaxis in general practice [2021]

Belgium

• BMC Public Health
  • Pre-exposure prophylaxis (PrEP) use trajectories and incidence of HIV and other sexually transmitted infections among PrEP users in Belgium: a cohort analysis of insurance claims data from 2017 to 2019 [2024]

Brazil

• Medicine
  • PrEP adopted by the brazilian national health system: What is the size of the demand? [2018]

• PLoS Neglected Tropical Diseases
  • HIV pre-exposure prophylaxis and incidence of sexually transmitted infections in Brazil, 2018 to 2022: An ecological study of PrEP administration, syphilis, and socioeconomic indicators [2023]

Burkina Faso

• Women's Health
  • Prevalence and factors associated with pre-exposure prophylaxis awareness among cisgender women of reproductive age in Burkina Faso [2024]

Canada

• Alberta Health Services
  • Alberta HIV Pre-Exposure Prophylaxis (PrEP) Guidelines

• Canadian Family Physician
  • Providing HIV preexposure prophylaxis [2022]
  • HIV preexposure prophylaxis in Canadian primary care and community settings [2019]

• Canadian HIV Trials Network
  • Canadian guideline on HIV pre-exposure prophylaxis and nonoccupational postexposure prophylaxis [2017]

• Canadian Journal of Infectious Diseases & Medical Microbiology
  • Clinical Considerations in the Selection of Preexposure Prophylaxis for HIV Prevention in Canada [2022]

• Public Health Agency of Canada
  • Setting the stage for expanding HIV pre-exposure prophylaxis use in Canada [2017]

Central Asia, Europe

• European Centre for Disease Prevention and Control
  • Pre-exposure prophylaxis for HIV prevention in Europe and Central Asia - Monitoring the implementation of the Dublin Declaration on partnership to fight HIV/AIDS in Europe and Central Asia: 2024 progress report (2023 data) [2025]
  • Evidence brief: Pre-exposure prophylaxis for HIV prevention in Europe and Central Asia - Monitoring implementation of the Dublin Declaration on Partnership to fight HIV/AIDS in Europe and Central Asia – 2020/2021 progress report [2022]
  • ECDC Evidence Brief: Pre-exposure prophylaxis for HIV prevention in Europe and Central Asia [2019]

• EuroSurveillance
  • Estimating the ‘PrEP Gap’: how implementation and access to PrEP differ between countries in Europe and Central Asia in 2019 [2019]

Eastern and Southern Africa

• WHO African Region
  • Improving the Quality of PrEP Implementation for Adolescent Girls and Young Women: An implementation brief to support programming in Eastern and Southern Africa [2021]

Europe

• Current Opinion in HIV and AIDS
  • The European preexposure prophylaxis revolution [2016]

• European Centre for Disease Prevention and Control
  • Monitoring HIV pre-exposure prophylaxis programmes in the EU/EEA [2022]
  • HIV Pre-Exposure Prophylaxis in the EU/EEA and the UK: implementation, standards and monitoring [2021]

• EuroSurveillance
  • Developing evidence-informed indicators to monitor HIV pre-exposure prophylaxis programmes across EU/EEA countries: a multi-stakeholder consensus [2023]
  • Options for affordable pre-exposure prophylaxis (PrEP) in national HIV prevention programmes in Europe [2017]
  • Meeting report: Pre-exposure Human Immunodeficiency Virus Prophylaxis in the EU/EEA: Challenges and Opportunities, Stockholm April 2016 [2016]

• Journal of the International AIDS Society
  • PrEP in Europe – expectations, opportunities and barriers [2016]

• Journal of Virus Eradication
  • Achievements and gaps to provide pre-exposure prophylaxis (PrEP) for women across the European Region – Results from a European survey study [2021]

Germany

• EuroSurveillance
  • Cost-effectiveness and budget effect of pre-exposure prophylaxis for HIV-1 prevention in Germany from 2018 to 2058 [2019]

• Infection
  • Low incidence of HIV infection and decreasing incidence of sexually transmitted infections among PrEP users in 2020 in Germany [2023]

• PLoS ONE
  • HIV Pre-exposure Prophylaxis (PrEP): Knowledge, attitudes and counseling practices among physicians in Germany – A cross-sectional survey [2021]

International

• AIDS and Behavior
  • The PrEP Care Continuum among Cisgender Women who Sell Sex and/or use Drugs Globally: A Systematic Review [2020]

• AIDS Research and Therapy
  • Low clinical impact of HIV drug resistance mutations in oral pre-exposure prophylaxis: a systematic review and meta-analysis [2024]

• EClinicalMedicine
  • Preferences for pre-exposure prophylaxis for HIV: A systematic review of discrete choice experiments [2022]

• IeDEA
  • Preexposure prophylaxis availability among health facilities participating in the global International epidemiology Databases to Evaluate AIDS (IeDEA) consortium [2024]

• International Journal of Environmental Research and Public Health
  • Current Perspectives on the Determinants of Acceptability of Pre-Exposure Prophylaxis and Nonoccupational Post-Exposure Prophylaxis among People at Risk for HIV: A Scoping Review [2022]

• International Journal of Infectious Diseases
  • Epub 2023 Jan 20. Determining the screening frequency for sexually transmitted infections for people who use HIV pre-exposure prophylaxis: a systematic review and meta-analysis [2023]

• Journal of the International AIDS Society
  • Missed opportunities for sexually transmitted infections testing for HIV pre-exposure prophylaxis users: a systematic review [2021]
  • Getting youth PrEPared: adolescent consent laws and implications for the availability of PrEP among youth in countries outside of the United States [2019]

• Lancet HIV
  • The Initiation, Discontinuation and Re-Starting of HIV Pre-exposure Prophylaxis (PrEP): An Ongoing Evolution of Implementation Strategies [2021]
  • Adoption of guidelines on and use of oral pre-exposure prophylaxis: a global summary and forecasting study [2021]

• PharmacoEconomics
  • Costs and Cost-Effectiveness of Biomedical, Non-Surgical HIV Prevention Interventions: A Systematic Literature Review [2023]

• Revista Brasileira de Enfermagem
  • Barriers to Pre-Exposure Prophylaxis (PrEP) use for HIV: an integrative review [2023]

• Sexually Transmitted Infections
  • Missed opportunities for guidance on sexually transmitted infection services: a global review of national HIV PrEP guidance [2024]

• UNAIDS
  • Oral pre-exposure prophylaxis–putting a new choice in context [2015]

• Viruses
  • Breakthrough Acute HIV Infections among Pre-Exposure Prophylaxis Users with High Adherence: A Narrative Review [2024]

Ireland

• Health Information and Quality Authority
  • Oral pre-exposure prophylaxis (PrEP) to prevent HIV: a systematic review and meta-analysis of clinical effectiveness, safety, adherence and risk compensation in all populations [2022]
  • HTA of a PrEP programme [2019]

• HIV Ireland
  • PrEP for Ireland

• Value in Health
  • Cost-Effectiveness Analysis of a National Pre-Exposure Prophylaxis (PrEP) Program in Ireland [2021]

Ireland, United Kingdom

• British Journal of General Practice
  • Pre-exposure prophylaxis and primary care [2020]

• EuroSurveillance
  • Minimum dataset for monitoring national human immunodeficiency virus pre-exposure prophylaxis (HIV PrEP) programmes: a five-nation consensus, 2019 [2021]

Israel

• Israel Medical Association Journal
  • Pre-Exposure Prophylaxis as a Method for Prevention of Human Immunodeficiency Virus Infection [2016]

Italy

• Acta Biomedica
  • The Italian PrEPventHIV challenge: a scoping systematic review on HIV pre-exposure prophylaxis monitoring in Italy [2022]

Kenya

• BMC Health Services Research
  • Low costs and opportunities for efficiency: a cost analysis of the first year of programmatic PrEP delivery in Kenya’s public sector [2021]

Latin America

• Journal of the International AIDS Society
  • Towards a fair consideration of PrEP as part of combination HIV prevention in Latin America [2016]

Latin America and the Caribbean

• Pan American Health Organization
  • Needs Estimation and Costing Tool for Implementing HIV Pre-exposure Prophylaxis (PrEP). User Guide [2022]

Low and middle income countries

• BMJ Global Health
  • Lessons learnt from daily oral PrEP delivery to inform national planning for PrEP ring introduction for women in low-income and middle-income countries: a qualitative inquiry of international stakeholders [2024]
  • Interventions to increase the uptake and continuation of pre-exposure prophylaxis (PrEP) by adolescent girls and young women at high risk of HIV in low-income and middle-income countries: a scoping review [2022]

• Centers for Disease Control and Prevention
  • Progress Toward UNAIDS Global HIV Pre-Exposure Prophylaxis Targets: CDC-Supported Oral Pre-Exposure Prophylaxis — 37 Countries, 2017-2023 [2024]
  • Expansion of HIV Preexposure Prophylaxis to 35 PEPFAR-Supported Early Program Adopters, October 2016–September 2018 [2020]

Namibia

• PLoS ONE
  • PrEP uptake and early persistence among adolescent girls and young women receiving services via community and hybrid community-clinic models in Namibia [2023]

New Zealand

• Best Practice Advocacy Centre New Zealand
  • HIV pre- and post-exposure prophylaxis: a guide for primary care [2024]

• New Zealand Sexual Health Society
  • PrEP and PEP Guidelines for Aotearoa New Zealand [2024]

Nigeria

• AIDS
  • Modelling the impact and cost-effectiveness of combination prevention amongst HIV serodiscordant couples in Nigeria [2015]

Republic of Korea

• Infection & Chemotherapy
  • Summary of Guidelines for the Use of Pre-Exposure Prophylaxis for HIV in Korea [2017]

South Africa

• BMC Medicine
  • Comparative effectiveness and cost-effectiveness of antiretroviral therapy and pre-exposure prophylaxis for HIV prevention in South Africa [2014]

• Journal of Infectious Diseases
  • Potential Clinical and Economic Value of Long-Acting Preexposure Prophylaxis for South African Women at High-Risk for HIV Infection [2015]

• PLoS ONE
  • Estimating the Cost-Effectiveness of Pre-Exposure Prophylaxis to Reduce HIV-1 and HSV-2 Incidence in HIV-Serodiscordant Couples in South Africa [2015]

• Southern African HIV Clinicians Society
  • Southern African guidelines on the safe, easy and effective use of pre-exposure prophylaxis: 2020 [2020]
  • Southern African guidelines on the safe use of pre-exposure prophylaxis in persons at risk of acquiring HIV-1 infection [2016]

South Africa, United States

• Journal of the International AIDS Society
  • Preventing HIV among adolescents with oral PrEP: observations and challenges in the United States and South Africa [2016]

Sub-Saharan Africa

• BMC Women's Health
  • Barriers to PrEP use and adherence among adolescent girls and young women in Eastern, Southern, and Western Africa: a scoping review [2024]

• BMJ Open
  • Service delivery models that promote linkages to PrEP for adolescent girls and young women and men in sub-Saharan Africa: a scoping review [2023]

• Journal of Infectious Diseases
  • Population-Level Correlation Between Incidence of Curable Sexually Transmitted Infections and Human Immunodeficiency Virus (HIV)-1 Among African Women Participating in HIV-1 Pre-Exposure Prophylaxis Trials [2022]

• Journal of the International AIDS Society
  • Characterizing populations prioritized for PrEP in 19 African countries: a review of national guidance [2025]
  • HIV PrEP is more than ART-lite: Longitudinal study of real-world PrEP services data identifies missing measures meaningful to HIV prevention programming [2021]
  • The impact, cost and cost-effectiveness of oral pre-exposure prophylaxis in sub-Saharan Africa: a scoping review of modelling contributions and way forward [2019]
  • PrEP as a feature in the optimal landscape of combination HIV prevention in sub-Saharan Africa [2016]

• Lancet HIV
  • Scaling up access to HIV pre-exposure prophylaxis (PrEP): should nurses do the job? [2022]

• Pan African Medical Journal
  • The effectiveness of tenofovir-based pre-exposure prophylaxis for prevention of HIV acquisition among sub-Saharan African women at high risk: a systematic review [2021]

• PLoS Medicine
  • Estimating HIV pre-exposure prophylaxis need and impact in Malawi, Mozambique and Zambia: A geospatial and risk-based analysis [2021]

Switzerland

• Federal Office of Public Health
  • Recommendations of the Swiss Federal Commission for Sexual Health (FCSH) on pre-exposure prophylaxis (PrEP) for HIV prevention [2016]

Taiwan

• Journal of Microbiology, Immunology and Infection
  • Taiwan guideline on oral pre-exposure prophylaxis for HIV prevention – 2018 update [2019]

Tanzania

• Annals of Global Health
  • Pre-exposure Prophylaxis Awareness and Endorsement among Adolescents and Young Adults in Tanzania: Insights from the 2022 Demographic and Health Survey [2025]

Thailand

• Journal of the International AIDS Society
  • HIV pre-exposure prophylaxis and health and community systems in the Global South: Thailand case study [2015]

Uganda

• Ministry of Health Uganda
  • Change package for Improving Uptake and Continuity on Pre-Exposure Prophylaxis (PrEP) [2023]
  • Technical Guidance on Pre-Exposure Prophylaxis (PrEP) for Persons at Substantial Risk of HIV Infection in Uganda [2022]

United Kingdom

• British HIV Association
  • BHIVA/BASHH guidelines on the use of HIV pre-exposure prophylaxis (PrEP) 2018 [2019]
  • The British HIV Association/British Association for Sexual Health and HIV Position Statement on pre-exposure prophylaxis in the UK [2012]

• Department of Health and Social Care
  • Roadmap for meeting the PrEP needs of those at significant risk of HIV

• EuroSurveillance
  • Current experiences of accessing and using HIV pre-exposure prophylaxis (PrEP) in the United Kingdom: a cross-sectional online survey, May to July 2019 [2019]

• Lancet HIV
  • HIV pre-exposure prophylaxis and its implementation in the PrEP Impact Trial in England: a pragmatic health technology assessment [2023]

• Public Health Scotland
  • Implementation of HIV Pre-Exposure Prophylaxis (PrEP) in Scotland: Minimum Dataset Reporting, 1 July 2017 to 31 December 2019

• Sexually Transmitted Infections
  • Impact of national commissioning of pre-exposure prophylaxis (PrEP) on equity of access in England: a PrEP-to-need ratio investigation [2024]

• UK Health Security Agency
  • HIV pre-exposure prophylaxis (PrEP): monitoring and evaluation

United States

• Agency for Healthcare Research and Quality
  • Preexposure Prophylaxis for the Prevention of HIV: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force [2023]

• AIDS
  • Systematic review of alternative HIV preexposure prophylaxis care delivery models to improve preexposure prophylaxis services [2023]

• AIDS and Behavior
  • Telehealth Models for PrEP Delivery: A Systematic Review of Acceptability, Implementation, and Impact on the PrEP Care Continuum in the United States [2024]
  • Pharmacy-Based Interventions to Increase Use of HIV Pre-exposure Prophylaxis in the United States: A Scoping Review [2022]

• AIDS Education and Prevention
  • What Predicts a Clinical Discussion About PrEP? Results From Analysis of a U.S. National Cohort of HIV-Vulnerable Sexual and Gender Minorities [2022]

• AIDS Patient Care and STDs
  • Health Care Provider Barriers to HIV Pre-Exposure Prophylaxis in the United States: A Systematic Review [2020]
  • Oral Pre-Exposure Prophylaxis (PrEP) for Prevention of HIV in Serodiscordant Heterosexual Couples in the United States: Opportunities and Challenges [2014]

• American College of Obstetricians and Gynecologists
  • Preexposure Prophylaxis for the Prevention of Human Immunodeficiency Virus [2022]

• Annals of Internal Medicine
  • Cost-Effectiveness of Long-Acting Injectable HIV Preexposure Prophylaxis in the United States : A Cost-Effectiveness Analysis [2022]

• Archives of Sexual Behavior
  • Pre-Exposure Prophylaxis (PrEP) for HIV Infection in Cisgender and Transgender Women in the U.S.: A Narrative Review of the Literature [2021]

• BMJ Open
  • Demographic, clinical guideline criteria, Medicaid expansion and state of residency: a multilevel analysis of PrEP use on a large US sample [2022]

• Centers for Disease Control and Prevention
  • Identifying Best Practices for Increasing HIV Pre-exposure Prophylaxis (PrEP) Use and Persistence in the United States: A Systematic Review [2024]
  • Racial, Ethnic, and Gender Disparities in Awareness of Preexposure Prophylaxis Among HIV-Negative Heterosexually Active Adults at Increased Risk for HIV Infection — 23 Urban Areas, United States, 2019 [2021]
  • Preexposure prophylaxis for the prevention of HIV infection in the United States – 2021 update clinical providers’ supplement [2021]
  • Preexposure prophylaxis for the prevention of HIV infection in the United States -- 2021 update : a clinical practice guideline [2021]
  • HIV Preexposure Prophylaxis Awareness and Referral to Providers Among Hispanic/Latino Persons — United States, 2019 [2021]
  • Preexposure Prophylaxis for Prevention of HIV Acquisition Among Adolescents: Clinical Considerations, 2020 [2020]
  • Vital Signs: Status of Human Immunodeficiency Virus Testing, Viral Suppression, and HIV Preexposure Prophylaxis — United States, 2013–2018 [2019]
  • Improving HIV Preexposure Prophylaxis Implementation for Women: Summary of Key Findings From a Discussion Series with Women's HIV Prevention Experts [2019]
  • HIV Preexposure Prophylaxis, by Race and Ethnicity — United States, 2014–2016 [2018]
  • HIV Preexposure Prophylaxis in the U.S. Military Services — 2014–2016 [2018]

• Clinical Infectious Diseases
  • US Guideline Criteria for Human Immunodeficiency Virus Preexposure Prophylaxis: Clinical Considerations and Caveats [2019]

• Expert Opinion on Drug Delivery
  • Long-acting HIV pre-exposure prophylaxis (PrEP) approaches: recent advances, emerging technologies, and development challenges [2022]

• Frontiers in Public Health
  • Access to PrEP and other sexual health services for cisgender women in the United States: a review of state policy and Medicaid expansion [2024]

• Inquiry
  • Recommendations for Increasing Physician Provision of Pre-Exposure Prophylaxis: Implications for Medical Student Training [2021]

• Journal of Acquired Immune Deficiency Syndromes
  • Determinants of Implementation for HIV Pre-exposure Prophylaxis Based on an Updated Consolidated Framework for Implementation Research: A Systematic Review [2022]

• Journal of Primary Care & Community Health
  • Pre-Exposure Prophylaxis Training among Medical Schools in the United States [2021]

• Journal of the American Board of Family Medicine
  • Preexposure Prophylaxis (PrEP) for HIV Prevention: The Primary Care Perspective [2016]

• Medical Surveillance Monthly Report
  • Guest editorial: health policy analysis on improving HIV PrEP implementation to help end the HIV epidemic in the U.S. military [2024]

• New York State Department of Health AIDS Institute
  • PrEP to Prevent HIV and Promote Sexual Health [2022]

• PLoS Medicine
  • Pre-exposure prophylaxis for preventing acquisition of HIV: A cross-sectional study of patients, prescribers, uptake, and spending in the United States, 2015–2016 [2020]

• PLoS ONE
  • Potential contribution of PrEP uptake by adolescents 15-17 years old to achieving the "Ending the HIV Epidemic" incidence reduction goals in the US South [2023]
  • PrEP implementation by local health departments in US cities and counties: Findings from a 2015 assessment of local health departments [2018]

• Society for Adolescent Health and Medicine
  • HIV Pre-Exposure Prophylaxis Medication for Adolescents and Young Adults: A Position Paper of the Society for Adolescent Health and Medicine [2018]

• StatPearls
  • Preexposure Prophylaxis for HIV Prevention

• U.S. Preventive Services Task Force
  • Prevention of Acquisition of HIV: Preexposure Prophylaxis [2023]

• Women's Health
  • US Black cisgender women and pre-exposure prophylaxis for human immunodeficiency virus prevention: A scoping review [2022]

• Women's Health Issues
  • No Longer the Exception, but the Standard: Integrating Trauma-Informed Policy and Pre-exposure Prophylaxis Implementation for Women [2021]

WHO

• World Health Organization
  • HIV drug resistance surveillance in countries scaling up pre-exposure prophylaxis, second edition [2025]
  • WHO implementation tool for pre-exposure prophylaxis of HIV infection: provider module for oral and long-acting PrEP [2024]
  • WHO implementation tool for pre-exposure prophylaxis (PrEP) of HIV infection: module 13: integrating STI services [2022]
  • Differentiated and simplified pre-exposure prophylaxis for HIV prevention: update to WHO implementation guidance [2022]
  • HIV drug resistance surveillance in countries scaling up pre-exposure prophylaxis [2020]
  • WHO implementation tool for pre-exposure prophylaxis (PrEP) of HIV infection: module 5: monitoring and evaluation [2018]
  • WHO implementation tool for pre-exposure prophylaxis (PrEP) of HIV infection: module 12: adolescents and young adults [2018]
  • Appropriate medicines: options for pre-exposure prophylaxis [2018]
  • WHO implementation tool for pre-exposure prophylaxis (PrEP) of HIV infection: module 9: strategic planning [2017]
  • WHO implementation tool for pre-exposure prophylaxis (PrEP) of HIV infection: module 8: site planning [2017]
  • WHO implementation tool for pre-exposure prophylaxis (PrEP) of HIV infection: module 6: pharmacists [2017]
  • WHO implementation tool for pre-exposure prophylaxis (PrEP) of HIV infection: module 4: leaders [2017]
  • WHO implementation tool for pre-exposure prophylaxis (PrEP) of HIV infection: module 3: counsellors [2017]
  • WHO implementation tool for pre-exposure prophylaxis (PrEP) of HIV infection: module 2: community educators and advocates [2017]
  • WHO implementation tool for pre-exposure prophylaxis (PrEP) of HIV infection: module 1: clinical [2017]
  • WHO implementation tool for pre-exposure prophylaxis (PrEP) of HIV infection: module 11: PrEP users [2017]
  • WHO implementation tool for pre-exposure prophylaxis (PrEP) of HIV infection: module 10: testing providers [2017]
  • Guidance on oral pre-exposure prophylaxis for serodiscordant couples, men and transgender women who have sex with men at high risk of HIV: recommendations for use in the context of demonstration projects [2012]
  • Guidance on Pre-exposure oral prophylaxis for serodiscordant couples, men who have sex with men and transgender women at high risk of HIV in implementation research, Annexes [2012]
  • Report of a consultation: preparing for pre-exposure prophylaxis (PrEP) results: from research to implementation [2010]
  • WHO implementation tool for pre-exposure prophylaxis (PrEP) of HIV infection
  • Pre-exposure prophylaxis (PrEP)
  • Global PrEP Network

Zambia

• BMJ Open
  • Initial implementation of PrEP in Zambia: health policy development and service delivery scale-up [2021]

• Global Health: Science and Practice
  • Addressing the Need for a Preexposure Prophylaxis Monitoring and Evaluation Implementation Guide: Experience From Zambia [2023]

{Related topics}

• Topic
  • Antiretroviral therapy